Body

随着年龄的增长,生蛇的严重程度和并发症的风险会随之增加。 1 大多数人都能完全康复。然而此病况仍会影响日常生活作息。2

生蛇引起的剧烈疼痛红疹会显著干扰日常生活,影响工作能力、情绪和生活质量,有时甚至会导致社交孤立和抑郁。2 此外,治疗费用和因病缺勤带来的经济负担也可能相当沉重。2

部分患者也可能会面临长期并发症。约 5 分之 1 生蛇患者可能面临带状疱疹后神经痛 ,3 这也是最常见的生蛇并发症。3,4 神经痛引起的疼痛可能非常严重,并且在皮疹消失后, 疼痛可持续数月至数年之久,3,4 以至于会影响日常生活。5

当生蛇出现在脸部时,病毒有高达25%的几率会蔓延至眼睛。导致‘眼部带状疱疹’(HZO)。6在罕见的情况下,若不及时处理,甚至可能导致视力受损或失明。6

其他并发症包括:皮肤疤痕、继发感染、听力丧失、在极少数情况下,它可能导致肺炎、脑炎和中风。 3,4

参考资料:
1. Centers for Disease Control and Prevention. Shingles facts and stats. Available at: https://www.cdc.gov/shingles/data-research/index.html. Accessed 17 September 2025.
2. Gater, A., et al. (2015). The humanistic, economic and societal burden of herpes zoster in Europe: A critical review. BMC Public Health, 15, 193.
3. Centers for Disease Control and Prevention. Shingles symptoms and complications. Available at: https://www.cdc.gov/shingles/signs-symptoms/index.html. Accessed 17 September 2025.
4. World Health Organization. Shingles (herpes zoster): Fact sheets. Available at: https://www.who.int/news-room/fact-sheets/detail/shingles-(herpes-zoster). Accessed 17 September 2025.
5. Oster, G., et al. (2005). Pain, medication use, and health-related quality of life in older persons with postherpetic neuralgia: results from a population-based survey. Journal of Pain, 6, 356–363.
6. Shaikh, S. & Ta, C. N. (2002). Evaluation and management of herpes zoster ophthalmicus. American Family Physician, 66, 1723–1730.

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